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The glucagon receptor activation changes how your body processes dietary fat, and combining that with the gastric slowing from GLP-1 agonism creates a perfect storm for nausea
demand growth [2]
Electrolyte replacement becomes important if diarrhea is significant
The most common: transient flushing or headache in the first 23 administrations as vasodilation occurs, and mild water retention (12 kg) within the first month
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