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Although inflammation can be a protective response, sustained activation of neuroinflammatory pathways leads to neuronal injury and causes the progression of neurodegenerative disorders ( 2.5 Impaired protein degradation systems Dysfunction in systems responsible for protein degradation, such as the ubiquitin-proteasome system (UPS) and autophagy, contributes to the development of AD and PD

Pratley RE, Crowley MJ, Gislum M, et al

This distinction has made Sermorelin particularly interesting within research domains focused on signal timing, feedback coordination, and peptide-mediated endocrine orchestration