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Tactile sensation (test of large fibers) is assessed at the 1st, 3rd and 5th metatarsophalangeal joints on the plantar side of the foot using a 10 g monofilament (always avoiding areas of hyperkeratosis, if present)

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The authors noted that children with serum zinc below 65 mcg/dL appeared to respond more favorably to amphetamine dose optimization when zinc was corrected, suggesting baseline zinc status may itself modulate stimulant drug response

With spending projections expecting continued sharp increases, PBMs have an important role to play in shaping prescription patterns more aligned with medical evidence (including trial data, treatment guidelines, medical best practices, etc.) and comparative research rather than drug maker promotional agendas