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This mechanism increases nitric oxide production, which is essential for endothelial cell proliferation, vessel dilation, and new capillary formation
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On the hair side, you might notice increased daily shedding not the typical 50100 hairs everyone loses, but noticeably more
This matters most for patients experiencing side effects at standard escalation rates or those who respond exceptionally well at lower doses
In the SURMOUNT-1 phase 3 trial (Jastreboff AM et al., N Engl J Med
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