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For the majority of the analyses, only the placebo and semaglutide 2.4 mg arms from the STEP 2 trial were analyzed ( n = 395)
Tirzepatide (Zepbound) is FDA approved for moderate to severe obstructive sleep apnea in adults with obesity, and it can meaningfully reduce apnea severity alongside substantial weight loss
People taking placebo in the study (not on medicine) lost an average of ~2.5% body weight (or about 6 lb)
Orforglipron , 35
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