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However, eNOS is also expressed in erythrocytes, and erythrocyte-derived NO may impact their deformability and suppress platelet activation [171, 172]

Prior plant studies support the plausibility of this approach where stress combined with epigenetic perturbation has been shown to increase extrachromosomal retrotransposon DNA and mobilization outputs, and long-read eccDNA profiling under epigenetic stress has revealed dramatic, family-specific bursts of eccDNA production (Thieme et al., 2017