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104 Similarly, Bolam et al.s 9-month combined exercise intervention (upper-body resistance + varying doses of impact loading) in middle-aged and elderly obese men revealed minimal changes ( 1%) in whole-body, lumbar spine and femoral neck BMD, with no between-group differences in bone turnover markers (BAP and CTX-1)

Instead, it identifies genetic predispositions that should be interpreted alongside clinical biomarkers, age, metabolic health, and individual goals by a qualified healthcare provider

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