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An elevated relative abundance of aerobic or facultative anaerobic bacteria, such as Verrucomicrobia, alongside a reduced presence of anaerobic bacteria like Synergistetes and Lentisphaerae, contributes to the worsening of AIH progression [11]
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Future Directions Safety Studies Long-term monitoring is required to assess the late-onset safety profiles of JAK inhibitors and IL-15 inhibitors, particularly regarding infection risks and potential oncogenic effects
Pharmaceutical Research 2010
