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Hyposmia, or a diminished sense of smell, may precede the onset of motor symptoms by 10 to 20 years, making it a valuable early diagnostic indicator

Without enough B12, oxygen delivery is impaired, leading to low energy levels and fatigue

C.ChichlowskiM.BergB

6 Ferroptosis in relation to other modes of cell death Ferroptosis is a type of programmed cell death that is distinguished from apoptosis, necrotic apoptosis, autophagy, pyroptosis and cuproptosis in both morphological changes and biochemical functions