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[3] The doses used in these tendon studies typically ranged from 10 to 200 micrograms per kilogram of body weight, administered once daily, which when extrapolated to a 75-kilogram human would suggest a working range of approximately 200 to 500 micrograms per day
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The freeze-thaw cycle can cause protein aggregation and denaturation, reducing potency
10.1016/j.mayocp.2019.01.001 Mayo Clin
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