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Direct evidence for the effect of glucagon on lean mass is seen from clinical situations of glucagon excess, in the glucagonoma syndrome ( Future Perspectives/Conclusions In the search for an anti-obesity pharmacotherapeutic which can rival the weight loss effects of bariatric surgery, research and development of gut hormone co-agonists is gaining momentum
In ATTAIN-MAINTAIN, patients who had plateaued after injectable therapy switched to oral orforglipron, marketed as Foundayo
The thigh is another good option , especially for self-administration
Key cited studies: Teichman SL et al
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