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Readouts such as NAD + /NADH, PARP activity, SIRT1/3 target engagement, and AMPK phosphorylation should therefore be interpreted according to cell type and disease phase
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10.3390/ijms20236020 54
This deficiency may exacerbate mitochondrial dysfunction and contribute to the challenges associated with autism, such as impaired cognitive function, communication difficulties, and motor skill deficits
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