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The NICE-recommended approach involves starting with metformin as first-line therapy, then adding a second agent if HbA1c remains above target

These receptors are found throughout the brain's key areas that control: Hypothalamus - regulating hunger and satiety Hindbrain - managing feelings of fullness Midbrain and prefrontal cortex - orchestrating reward responses Brain stem - controlling various metabolic functions Scientists have discovered that semaglutide can improve cognitive function and protect against neurological conditions