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A Phase 2a trial in adults with metabolic dysfunction-associated steatotic liver disease (MASLD, a fat-related liver condition formerly called NAFLD) found that retatrutide reduced liver fat content by more than 80% at 48 weeks at the higher doses, with a meaningful share of patients reaching normal liver-fat levels
5 Tirzapetide (Mounjaro): 85% of study participants lost at least 5% body weight
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