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The majority of the studies (see above in red) are preclinical studies in rodents, the vast majority of which have been done by a single research group in Croatia, which has been rinsing and repeating the same approach for decades
1 2 "Cobalamin coenzyme forms are not likely to be superior to cyano- and hydroxyl-cobalamin in prevention or treatment of cobalamin deficiency"
Quality control comparable to a 503A or 503B compounding pharmacy is not present for research peptide vendors
However, the lack of human clinical trials means long-term safety in people remains unknown
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