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This design allows for a convenient and controlled application on the skin, ensuring that the active ingredients are localized for optimal treatment

At the standard escalation of 2.5 mg for 4 weeks then 5 mg, you would use 10 mg in the first month (4 doses at 2.5 mg) and then continue at 5 mg per week

Fly strains UAS-GFP (Bloomington Stock #6874), TH-Gal4 (Bloomington Stock #8848), CatalaseRNAi (Bloomington Stock #34020) and PHGPx (Bloomington Stock #33939), were obtained from Bloomington stock center, Indiana, along with park 13 (Bloomington Stock #79210) as the Parkinsonian disease model

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