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Phenotypic consequences of SLC25A40-ABCB1 fusions beyond drug resistance in high-grade serous ovarian cancer

Based on the final RSV concentration of 1 mg/mL, this administration regimen corresponded to a nominal RSV dose of approximately 3.33 mg/kg

5-Amino-1MQ is a substrate-mimetic inhibitor occupying the nicotinamide binding site, with a reported IC of 1.2 0.1 M (Neelakantan et al., J Med Chem, 2017)