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Chronic oral exposure to short chain chlorinated paraffins induced testicular toxicity by promoting NRF2-mediated oxidative stress
In vitro studies further revealed that schisandrin B suppressed oxidative stress and inflammation in BV2 microglia and PC12 cells [63, 64] and protected against microglial-mediated inflammatory damage in microglianeuron cocultures by downregulating NADPH oxidase and other mediators, such as NO, TNF-, PGE-2, IL-1 and IL-6 [37]
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