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Melanotan 2 interacts with several melanocortin receptors, including MC1R, MC3R, MC4R, and MC5R
Now it seems oral small-molecule GLP-1s also dial back eating for pleasure by engaging a brain reward circuit. Given the effect of these drugs on eating for pleasure, future studies could explore whether small-molecule GLP-1s can also suppress cravings for other addictive substances
Safety information The most common side effects include nausea, vomiting, diarrhea, and abdominal pain
References: [1] FDA clarifies policies for compounders as national GLP-1 supply begins to stabilize (Accessed August 2025)
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