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These medications: reduce appetite lower inflammation improve liver fat improve metabolic markers reduce cardiovascular events (SELECT trial) They do not : build muscle increase VO max improve mitochondrial function replace strength training fix metabolic flexibility guarantee long-term weight maintenance 2
[12] What little has appeared since is preclinical and mostly concerns engineered analogues rather than DSIP itself for instance, fusion constructs designed to survive in circulation and cross the blood-brain barrier, tested in chemically-induced insomnia models in mice
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