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NO also modestly reduces CYP51A1 mRNA expression, though the effect is less pronounced than the reduction at the protein level, further supporting a predominant role for post-translational control [43]

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Above its lower critical solution temperature (LCST, ~ 32 C), PNIPAM undergoes a coil-to-globule transition, causing the three-dimensional polymer network to shrink due to hydrophobic interactions [148]