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doi: 10.1016/j.clineuro.2009.04.001 130 FengYMadungweNBImam AliaganADTomboNBopassaJC
Synthesis From the starting material phenol, paracetamol can be made in the following manner: Phenol is nitrated using sulfuric acid and sodium nitrate (as phenol is highly activated, its nitration requires very mild conditions compared to the oleum-fuming nitric acid mixture required to nitrate benzene)
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