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Regulatory status is jurisdiction specific and may change
The compound consists of standard and modified amino acids forming a stable pentapeptide suitable for laboratory investigation
In an additional, 30-week placebo-controlled, study of patients with type 2 diabetes inadequately controlled with metformin comparing the maintenance of sitagliptin 100 mg versus withdrawal of sitagliptin when initiating basal insulin therapy, the event rate and incidence of documented symptomatic hypoglycemia (blood glucose measurement 70 mg/dL) did not differ between the sitagliptin and placebo groups
Helping patients understand the actions of these medications can alert them to the potential gastrointestinal (GI) side effects (see sidebar Tips to Minimize GI Side Effects below)
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