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La vacunacin est indicada en: pacientes con enfermedades hepticas o en tratamiento con: frmacos hepatotxicos, inmunodeprimidos, personal con riesgo ocupacional, viajeros a reas endmicas (al menos, 1 mes antes) y familiares de familia originaria de zonas de alta endemia
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Obesity-associated inflammation accelerates NAD consumption through activation of NAD-utilizing enzymes such as poly(ADP-ribose) polymerase 1 (PARP-1) and cluster of differentiation 38 (CD38) [85]
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