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Perhaps some of the same signaling pathways that play a role in addiction behavior and alcohol cravings are also affected
Approximately 20%-30% of individuals with MASLD progress to MASH, characterized by hepatocyte ballooning, lobular inflammation, and variable fibrosis, and 10%-20% of MASH patients develop advanced fibrosis (stages F3-F4) or cirrhosis over their lifetime [6,13]
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Gastrointestinal disorders, primarily nausea, were the most common treatment-emergent adverse events, which could be mitigated with slower dose escalation
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