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This is not simply due to supplements but also due to the widespread fortification of foods with folic acid and has been shown by some authors to lower the rates of macrocytosis in patients with proven B12 deficiency (Wyckoff)
The consequences range from subtle, such as gradual peptide degradation that skews dose-response curves, to overt, such as visible contamination that invalidates an entire experimental series
Surgical Interventions : When necessary, surgery can provide definitive solutions
Antioxidants & redox signaling, 30(2), 251294
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