tirzepatide gila monster venom… and weight loss? 🦎 It sounds wild, but it's true. GLP-1 medications were inspired by a hormone first discovered in the saliva of a Gila monster. On this week's Lessons from the Gila Monster:

Golor, F.L

Figure 3 below summarizes these processes, highlighting the interplay between bacterial infection, immune mediators (e.g., TNF-, IL-6, transforming growth factor-beta [TGF-], IL-10), and cellular actors (e.g., neutrophils, M1/M2 macrophages, fibroblasts, keratinocytes, endothelial cells) during wound healing [43, 48]

While these increases typically resolved or stabilized, they represent a unique variable for researchers to monitor

Numerous studies have investigated the expression patterns of endogenous GLP-1 and GLP-1R in the central nervous system (CNS) and the peripheral nervous system, with a consensus that these are expressed on neurons and found in most areas of the brain and gutbrain axis 2