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Typical protocols involve doses ranging from 13 mg daily or several times per week, often cycled in 812 week intervals with breaks to prevent receptor downregulation or potential copper accumulation

Vitamin D is crucial to the building and maintenance of healthy bones and teeth

BBB function was degraded in this model which reproduced the aspects of PD, including alpha-synuclein accumulation and mitochondrial impairment (Pediaditakis et al., 2021)

A High-Calcium and Phosphate Rescue Diet and VDR-Expressing Transgenes Normalize Serum Vitamin D Metabolite Profiles and Renal Cyp27b1 and Cyp24a1 Expression in VDR Null Mice