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For example, the addition of semaglutide at a dose of 0.5 mg or 1 mg per week in patients receiving basal insulin resulted in a 1% and 1.8% decrease in HbA1c, respectively, in SUSTAIN- 5
This can lead to a reduction in the signs of aging, such as wrinkles, fine lines, and age spots
The causes are multiple: metabolic changes, sleep disruption from GI symptoms, and changes in energy metabolism that affect sleep architecture
These effects have been found to have important implications for systemic inflammatory responses
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