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Mechanistic exploration suggested that pamidronate and clodronate markedly inhibit IGF-1-induced HIF-1 protein accumulation and VEGF expression in breast cancer cells via the PI-3K/AKT/mTOR signaling pathway and ultimately eliminate IGF-1-induced tumor angiogenesis in vivo and in vitro (38)
But microdosing isnt something to try on your own
A consultation will help determine whether this treatment is suitable for you, although testing can be arranged if needed
The 12.5mg total per vial provides enough semaglutide for a multi-week supply depending on dose
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