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Tirzepatide is a newer medication that activates two hormones instead of one : GLP-1 (Glucagon-Like Peptide-1) GIP (Glucose-Dependent Insulinotropic Polypeptide) Because it targets both hormone pathways, Tirzepatide can provide greater appetite control and improved metabolic support for many patients
Although individual responses vary, the consistency of findings strengthens the case for a modest hypertension benefit associated with GLP-1 therapy
Endocrinology 153 , 58575865 (2012)
doi: 10.1016/j.peptides.2024.171212 Summary Keywords GIP -glucose-dependent insulinotropic polypeptide, antagonism, obesity, diabetes, pharmacology Citation Koefoed-Hansen F, Helsted MM, Kizilkaya HS, Lund AB, Rosenkilde MM and Gasbjerg LS (2025) The evolution of the therapeutic concept GIP receptor antagonism
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