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This diminishment leads to weight gain, loss of muscle mass, and loss of energy
However, when APAP is ingested in excessive amounts, the capacity of GSH to neutralize NAPQI becomes overwhelmed, leading to depletion of hepatic GSH stores and accumulation of NAPQI, resulting in oxidative stress, mitochondrial dysfunction, and hepatocellular injury, ultimately culminating in acute liver injury and potential liver failure
Kade IJ, Balogun BD, Rocha JB
Normal sperm motility is around 55% to 75%, which decreases 5 to 10% on average per hour
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