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2.2 Methionine and mTOR pathway The mTOR serves as a central molecular hub that positively governs anabolic processes while simultaneously exerting negative regulation on certain catabolic pathways (Xie and Proud, 2013)

demonstrated that a patient with chronic RE experienced sustained relief from symptoms such as abdominal pain, diarrhoea, and haematochezia following two courses of intestinal microecological transplantation, accompanied by a shift in microbial diversity and composition towards the donors profile 179

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