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The occurrence of ferroptosis in mature erythrocytes has not been confirmed and it seems quite challenging, since ferroptosis studies suffer from the lack of well-established markers and evaluation of this cell death requires a complex approach with identification of typical cellular and subcellular morphological alterations, genetic hallmarks, biochemical changes, expression of certain ferroptosis-related proteins, etc
doi: 10.1038/s41564-025-01932-w 51 ZhangTHolmanJMcKinstryDTrindadeBCEatonKAMendoza-CastrejonJet al
If IV acetylcysteine is unavailable, then oral acetylcysteine may be used
DSIP 200 mcg subcutaneously, 30 minutes before bed
