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Progressive Enhancement : Your treatment plan evolves as your weight loss progresses: Initial focus may be preventative biostimulation with minimal fillers Mid-journey adjustments might include more targeted volume replacement Later stages often incorporate more intensive skin tightening Clinical Evidence Supporting Combined Approaches: The 2025 Galderma study specifically utilised a combined protocol where patients received: Sculptra and either Restylane Lyft or Contour for their first treatment A second Sculptra treatment with optional Restylane touch-up at Week 4 An optional third Sculptra treatment at Week 8 This integrated approach delivered impressive results: Significant improvements in facial contour and skin quality 85% of patients reporting a more refreshed appearance by Week 4 89% feeling more attractive with natural-looking results at three months Personalised Treatment Combinations by Patient Profile At Aestha Clinic, we create truly customised treatment plans that mix and match from our toolkit based on your unique needs

In health, GLP-1 stimulates the synthesis and secretion of insulin from pancreatic -cells in a glucose-dependent manner (i.e., it is activated when blood glucose levels are elevated, typically in the postprandial state)

One study showed that Akkermansia increased GLP-1 levels in human cells by over 2,000%

Encouraged by their success with the dual agonist, Tschp and DiMarchi wondered if it was possible to go a step further and develop a peptide to simultaneously target three key metabolically-related hormone receptors: GLP-1, GIP and glucagon