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2D and Table S1), which may be attributed to rigidification of the GSH surface ligands due to the HIP with DDA
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In the obese state, the iron-handling capacity of MFe hi macrophages is impaired, they become more pro-inflammatory
The subsequent antigen presentation triggers the activation of Th1 and Th17 cells, leading to the release of pro-inflammatory cytokines (IL-2, TNF-, IFN-, IL-17), which in turn amplify oxidative stress and perpetuate an amplifying loop of inflammation and tissue damage (Kubiak et al
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