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This process also contributes to the removal of damaged organelles, such as mitochondria and ER, and misfolded or aggregate-prone proteins (Mizushima, 2011)
The specific antisense sequences were 5-GGCUCCUACACUUCUGUUATT-3 for FoxO4 siRNA and 5-UAACAGAAGUGUAGGAGCCTT-3 for the negative control
TUNEL staining of renal tissues Mouse kidney biopsy paraffin sections were deparaffinized with xylene and ethanol to ablate peroxidase activity and stained with a TUNEL kit (A113, Vazyme, China) following the protocol of the product instructions
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