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Site rotation across these regions on a weekly basis is standard practice for all once-weekly subcutaneous peptide administrations, and is particularly important during extended retatrutide dosing studies where repeated injection at a single site can cause localized lipodystrophy or reduced absorption efficiency
Delayed gastric emptying affects oral drug absorption particularly for medications requiring timely uptake
Tirzepatide doses range from 2.5 mg to 15 mg
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