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Other MTHFR Symptoms by Body System Neurological Symptoms: Brain Fog, Anxiety, and Irritability MTHFR gene mutations can significantly impact your nervous system because methylation is essential for producing neurotransmitters like serotonin, dopamine, and norepinephrine the chemical messengers that regulate mood, focus, and mental clarity
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On the other hand, oral supplements must navigate through your digestive system, which can affect how much B12 your body absorbs
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