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"Triplehormone-receptor agonist retatrutide for obesitya phase 2 trial." New England Journal of Medicine 389.6 (2023): 514-526
For example, mapping the interactomes of HSP70 and HSP90 has clarified that these proteins not only ensure correct folding but also influence autophagic decision-making and UPS performance, 548,549 highlighting their integrative role in proteostasis governance
Experimental studies have demonstrated that chronic hyperglycemia may reduce -cell expression of GLP-1 receptors, leading to diminished responsiveness to endogenous GLP-1 [7, 10]
As research progresses, these molecules could lead to groundbreaking therapies, providing new hope for patients and healthcare providers alike
