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10.1182/blood-2008-03-040253 11 CarmelR.SarraiM
It is a triple agonist, targeting GLP-1, GIP, and glucagon receptors, three separate hormonal pathways working simultaneously to suppress appetite, accelerate fat metabolism, and improve insulin sensitivity
Macro- ATG consists in the delivery of cytoplasmic cargo to the lysosome through the intermediary of a double membrane bound vesicle, the autophagosome, which fuses with the lysosome to form an autolysosome (Zhang, 2013)
GLP-1 receptor activation slows gastric emptying, which can cause variable bowel changes including looser stools, diarrhoea, or constipation
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