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Distinct PI(3)Ks Mediate Mitogenic Signalling and Cell Migration in Macrophages
Quinacrine and niclosamide promote neurite growth in midbrain dopaminergic neurons through the canonical BMP-smad pathway and protect against neurotoxin and -Synuclein-Induced neurodegeneration
This process is facilitated by lysosomal iron release and its uptake into mitochondria, resulting in the induction of the mitochondrial permeability transition and ultimately hepatocyte necrosis
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