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Temperature fluctuations accelerate this degradation dramatically

Figure 2 Compartmentalization of glutathione biosynthesis is unique to plants (Noctor et al., Plant GlutamateCysteine Ligase: Structure, Function, and Regulation Glutamatecysteine ligase catalyzes the ATP-dependent formation of a peptide bond between glutamate and cysteine in the first reaction of glutathione synthesis

This exploratory, cross-sectional finding suggests a distinct role of oxidative stress in migraine pathophysiology

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