Placebo capsules comprised microcrystalline cellulose (REDWELLS HEALTH LTD, London, UK) combined with 10% (w/w) gum Arabic (CAS 9000-01-5, Willy Benecke, Hamburg, Germany), matching the gum Arabic content of the pomegranate extract, and 1% (w/w) brown food coloring (rainbow dust edible powder color, Cake Decorating Co., UK) to ensure that the pomegranate and placebo capsules were identical in appearance
347,348 By reducing afterload, vasodilators improve ventricular function and alleviate dyspnea by lowering cardiac filling pressures, making them a fundamental component of first-line HF therapy
Price variations between pharmacies can exceed $200 for identical medications, making comparison essential
10.1164/rccm.201307-1289LE Am J Respir Crit Care Med