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Foers AD, Chatfield S, Dagley LF, Scicluna BJ, Webb AI, Cheng L, Hill AF, Wicks IP, Pang KC (2018) Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography

(2018) showed that compared to wild-type mice, SHANK3- and SHANK2-knockout mice had fewer glutamate receptors in the striatum and thalamus regions, while CNTN4 knock-out mice had fewer glutamate receptors in the cortex and hippocampus regions [60]

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When severed nerves in animal models were placed in collagen tubes impregnated with GHK, researchers observed significantly increased nerve outgrowth, elevated production of nerve growth factor (NGF) and neurotrophins NT-3 and NT-4, accelerated regeneration of nerve fibers, and increased axon count and Schwann cell proliferation compared to controls