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2 Anti-fibrotic effect of SalB 2.1 Hepatic fibrosis Hepatic fibrosis (HF) is a common pathological feature seen in many etiologies of chronic liver disease and is an intermediate stage in the diseases progression (Tacke and Trautwein, 2015)
Its weakness is penetration, since copper peptides struggle to reach deeper layers without help, and many over-the-counter serums are underdosed anyway
Additionally, it supports angiogenesis and skin regeneration at the cellular level, resulting in visible improvement of skin structure and appearance
The LDL receptor spans the plasma membrane and it is the extracellular domain that is responsible for apoB-100/apoE binding
