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Medinas et al., 2018)

Figure 3 After the diagnosis of GSSD, the infant continued to receive l-carnitine to improve her metabolism, oral sodium bicarbonate to correct acidosis, and oral vitamins C and E to prevent oxidative stress

Future studies should optimize treatment parameters, including formulation, dosage, timing of administration, and assessment of brain biodistribution and explore multi-target strategies combining redox modulation with interventions that directly engage synaptic plasticity, neurotrophic signaling or critical developmental windows, to achieve functional behavioral outcomes in ASD

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