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Celebrities, including Elon Musk, have also said they take the drugs to shed pounds fueling skyrocketing interest

Kershner and Kimble, 2010

Contact your GP if constipation persists despite over-the-counter treatment for 12 weeks, or if you experience severe abdominal pain, rectal bleeding, unexplained weight loss, or persistent vomiting, as these may indicate complications requiring further investigation