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PD patients and animal models exhibit decreased CoQ 10 levels (100, 101)
The high cost and variable coverage of AOMs have also contributed to underutilization
Exposure to HO resulted in a + 64 Da mass shift, consistent with overoxidation of Cys10 to sulfinic acid, together with oxidation of two methionine residues in the sequence
Its not like the guy whos on 28 nM is on too much or the guy whos on a level of eight is on too little because thats where his body is set to. Prof McLachlan You can think of it like height perfectly healthy men can be 165cm or 205 cm, its just where you sit on the reference range
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