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However, approximately half of the patients undergoing endocrine therapy suffer relapses, including mutations in the ER coding gene ESR1 , especially the L536Q and Y537S mutations [6], which present a significant clinical challenge

Further details on the patient samples were provided in Supplementary Table 1

This microbial shift enhanced the activity of group 3 innate lymphoid cells (ILC3s), thereby promoting anti-inflammatory cytokines IL-22 and IL-10 (Sun et al., 2024)